BiologicalActivity
NMDAreceptormodulator.MetaboliteofKetaminehydrochloride(Cat.No.3131).DecreasesintracellularD-serineconcentration(IC50=91nM)andaltersserineracemaseexpressioninPC-12cells.Exhibitsanalgesiceffectsinratpainmodels.S-enantiomerandracematealsoavailable.
TechnicalData
| M.Wt | 260.16 |
| Formula | C12H14ClNO.HCl |
| Storage | DesiccateatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 83777-68-8 |
| PubChemID | 71743680 |
| InChIKey | CLPOJGPBUGCUKT-UTONKHPSSA-N |
| Smiles | ClC1=C([C@@]2(N)C(CCCC2)=O)C=CC=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 26.02 | 100 | |
| water | 26.02 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight260.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.84mL | 19.22mL | 38.44mL |
| 5mM | 0.77mL | 3.84mL | 7.69mL |
| 10mM | 0.38mL | 1.92mL | 3.84mL |
| 50mM | 0.08mL | 0.38mL | 0.77mL |
MolarityCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.