Biological Activity
Non-selective serotonin receptor agonist. Active metabolite of psilocybin; hallucinogen.
Technical Data
M. Wt | 204.27 |
Formula | C12H16N2O |
Storage | Store at -20°C |
Purity | ≥99% |
CAS Number | 520-53-6 |
PubChem ID | 4980 |
InChI Key | SPCIYGNTAMCTRO-UHFFFAOYSA-N |
Smiles | OC1=C2C(NC=C2CCN(C)C)=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
DMSO | 20.43 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 204.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 4.9 mL | 24.48 mL | 48.95 mL |
5 mM | 0.98 mL | 4.9 mL | 9.79 mL |
10 mM | 0.49 mL | 2.45 mL | 4.9 mL |
50 mM | 0.1 mL | 0.49 mL | 0.98 mL |
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References
References are publications that support the products' biological activity.
Merck Index 12 4629 PMID:
Almaula et al (1996) Contribution of a helix 5 locus to selectivity of hallucinogenic and nonhallucinogenic ligands for the human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors: direct and indirect effects on ligand affinity mediated by the sa Mol.Pharmacol. 50 34 PMID: 8700116
Lee and Roth (2012) Hallucinogen actions on human brain revealed. Proc.Natl.Acad.Sci.USA 109 1820 PMID: 22308478
Keywords: Psilocin, supplier, hallucinogenics, serotonin, serotonergics, 5-ht, receptors, nonselective, agonists, Non-selective, 5-HT, Tocris Bioscience