BiologicalActivity
EstrogenreceptorantagoNIST.Tamoxifen(Cat.No.0999)metabolite;exhibitsgreaterpotencythantheparentcompound.Chemotherapeuticagent.Alsoactivatesintein-linkedinactiveCas9,reducingoff-targetCRISPR-mediatedgeneediting;systemhas~25-foldhigherspecificitythanwtCas9.
TechnicalData
| M.Wt | 387.51 |
| Formula | C26H29NO2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 68047-06-3 |
| PubChemID | 449459 |
| InChIKey | TXUZVZSFRXZGTL-QPLCGJKRSA-N |
| Smiles | CCC(C3=CC=CC=C3)=C(C2=CC=C(OCCN(C)C)C=C2)/C1=CC=C(O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 38.75 | 100 | |
| ethanol | 19.38 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight387.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.58mL | 12.9mL | 25.81mL |
| 5mM | 0.52mL | 2.58mL | 5.16mL |
| 10mM | 0.26mL | 1.29mL | 2.58mL |
| 50mM | 0.05mL | 0.26mL | 0.52mL |
MolarityCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.