Tocris/PF 04628935/6347/5/5毫克
商品编号：
6347
市场价：
¥1380.00
美元价：
828.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:PotentghrelinreceptorinverseagoNIST
ChemicalName:1-[2-[[2-Chloro-4-(2H-1,2,3-triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentghrelinreceptorinverseagonist(IC50=4.6nM).Orallybioavailableandexhibitsreasonablebrainpenetration.
LicensingInformation
SoldforresearchpurposesunderagreementfromPfizerInc.
TechnicalData
| M.Wt | 496.03 |
| Formula | C24H26ClN7OS |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1383719-97-8 |
| PubChemID | 70682037 |
| InChIKey | MTDYDDJVCIHZKH-UHFFFAOYSA-N |
| Smiles | ClC1=C(CN2CC3(CCN(C(CC4=CN(C=C(C)S5)C5=N4)=O)CC3)C2)C=CC(N6N=CC=N6)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 24.8 | 50 | |
| ethanol | 9.92 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight496.03.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.02mL | 10.08mL | 20.16mL |
| 5mM | 0.4mL | 2.02mL | 4.03mL |
| 10mM | 0.2mL | 1.01mL | 2.02mL |
| 50mM | 0.04mL | 0.2mL | 0.4mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.