BiologicalActivity
5-HT2Aandα1adrenoceptorantagonist.EnhancesneuronaldifferentiationofmouseandhumanneuralProgenitorcells.AlsoinhibitsPERK/eIF2α-P-mediatedreductioninproteinsynthesisandrestoresmemorydeficitsinamousedementiamodel.Antidepressantandneuroprotectant.
TechnicalData
M.Wt | 408.32 |
Formula | C19H22ClN5O.HCl |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 25332-39-2 |
PubChemID | 62935 |
InChIKey | OHHDIOKRWWOXMT-UHFFFAOYSA-N |
Smiles | ClC1=CC=CC(N2CCN(CC2)CCCN3N=C4C=CC=CN4C3=O)=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 20.42 | 50 | |
water | 8.17 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight408.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.45mL | 12.25mL | 24.49mL |
5mM | 0.49mL | 2.45mL | 4.9mL |
10mM | 0.24mL | 1.22mL | 2.45mL |
50mM | 0.05mL | 0.24mL | 0.49mL |
MolarityCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.