Tocris/AM 4113/6193/10/10毫克
商品编号：
6193
市场价：
¥2500.00
美元价：
1500.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:Selective,highaffinityCB1antagoNIST
ChemicalName:5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
HighaffinityandselectiveCB1antagonist(Kd=0.89nM).Exhibits100-foldselectivityforCB1overCB2.AttenuatesCB1agonistAM411-inducedlocomotorsuppressionandreducesfoodintakeinvivo,butdoesnotinducesignsofnausea.
TechnicalData
| M.Wt | 380.66 |
| Formula | C17H12Cl3N3O |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 614726-85-1 |
| PubChemID | 66844170 |
| InChIKey | BBUKVPCUOHFAQN-UHFFFAOYSA-N |
| Smiles | CC1=C(C2=CC=C(C=C2)Cl)N(C3=C(C=C(C=C3)Cl)Cl)N=C1C(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 7.61 | 20 | |
| ethanol | 7.61 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight380.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.63mL | 13.14mL | 26.27mL |
| 5mM | 0.53mL | 2.63mL | 5.25mL |
| 10mM | 0.26mL | 1.31mL | 2.63mL |
| 50mM | 0.05mL | 0.26mL | 0.53mL |
MolarityCalculator
MolarityCalculator
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ReconstitutionCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.