Tocris/M62812/5705/10/10 mg
商品编号：
5705
市场价：
¥2300.00
美元价：
1380.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:TLR-4inhibitor
ChemicalName:6-(2-Aminophenoxy)-1,2-benzisothiazol-3-aminedihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
TLR4inhibitor.InhibitsLPS-inducedNF-κBactivationinHEK293cells(IC50=2.4μg/mL).AlsoinhibitsLPS-inducedcytokineproductionandprocoagulanteffectsinPBMCsandHUVECs.Prolongssurvivalinamousesepticshockmodel.
TechnicalData
| M.Wt | 330.23 |
| Formula | C13H11N3OS.2HCl |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 613263-00-6 |
| PubChemID | 44224214 |
| InChIKey | SMTKPLISDFNJDJ-UHFFFAOYSA-N |
| Smiles | NC1=CC=CC=C1OC2=CC=C3C(SN=C3N)=C2.Cl.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 16.51 | 50 | |
| water | 33.02 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight330.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.03mL | 15.14mL | 30.28mL |
| 5mM | 0.61mL | 3.03mL | 6.06mL |
| 10mM | 0.3mL | 1.51mL | 3.03mL |
| 50mM | 0.06mL | 0.3mL | 0.61mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.