Tocris/SKI 178/5452/10/10毫克
商品编号：
5452
市场价：
¥1980.00
美元价：
1188.00
产品分类：
其它酶
公司分类：
Other_enzymes
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:Non-lipidsphingosinekinase1(SphK1)inhibitor
ChemicalName:N'-(1-(3,4-Dimethoxyphenyl)ethylidene)-3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Non-lipidsphingosinekinase1(SphK1)inhibitor(IC50=0.1-1.8μM).InducesCDK1-dependentapoptosisinhumanacutemyeloidleukemiacelllines.Activeinvivo.
TechnicalData
| M.Wt | 394.42 |
| Formula | C21H22N4O4 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1259484-97-3 |
| PubChemID | 5342941 |
| InChIKey | GMFUWEBOUKIKRP-LPYMAVHISA-N |
| Smiles | O=C(N/N=C(C)/C1=CC=C(OC)C(OC)=C1)C2=CC(C3=CC=C(OC)C=C3)=NN2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 39.44 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight394.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.54mL | 12.68mL | 25.35mL |
| 5mM | 0.51mL | 2.54mL | 5.07mL |
| 10mM | 0.25mL | 1.27mL | 2.54mL |
| 50mM | 0.05mL | 0.25mL | 0.51mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.