Tocris/Ascomycin/4210/1/1mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Ascomycin/4210/1/1mg

Tocris/Ascomycin/4210/1/1mg

商品编号： 4210/1

品牌： Tocris Bioscience

市场价： ¥3300.00

美元价： 1980.00

产地：美国(厂家直采)

公司：

产品分类：蛋白酶类

公司分类： protease

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Calcineurinphosphataseinhibitor;analogofFK506(Cat.No.3631)

AlternativeNames:FK520,FR900520

ChemicalName:(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AnalogofFK506(Cat.No.3631);bindstoFK506-bindingprotein12(FKBP12)inordertoinhibitcalcineurinphosphataseactivity(IC₅₀=49nM)andactivationofnuclearfactorofactivatedTcells(NFAT).Displaysantifungalandimmunosuppressiveactivities.

TechnicalData

M.Wt	792.01
Formula	C₄₃H₆₉NO₁₂
Storage	Storeat-20°C
CASNumber	104987-12-4
PubChemID	5282071
InChIKey	ZDQSOHOQTUFQEM-NURRSENYSA-N
Smiles	O[C@H]1[C@H](OC)C[C@H](/C=C(C)/[C@@H](O4)[C@H](C)[C@@H](O)CC([C@H](CC)/C=C(C)/C[C@H](C)C[C@H](OC)[C@@]2([H])O[C@](C(C(N3[C@@](C4=O)([H])CCCC3)=O)=O)(O)[C@H](C)C[C@@H]2OC)=O)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	39.6	50
	ethanol	39.6	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight792.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.26mL	6.31mL	12.63mL
5mM	0.25mL	1.26mL	2.53mL
10mM	0.13mL	0.63mL	1.26mL
50mM	0.03mL	0.13mL	0.25mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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