Tocris/BAY 41-2272/4430/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/BAY 41-2272/4430/50/50 mg

Tocris/BAY 41-2272/4430/50/50 mg

商品编号： 4430/50

品牌： Tocris Bioscience

市场价： ¥16500.00

美元价： 9900.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Solubleguanylylcyclase(sGC)activator

ChemicalName:5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Activatorofsolubleguanylylcyclase(sGC);actsatanitricoxide(NO)-independentregulatorysiteinthesGCα₁subunit.Inhibitsplateletaggregation(IC₅₀=36nM)andphenylephrine-inducedcontractionsofrabbitaorta(IC₅₀=0.30μM).AlsoreducesvascularsmoothmusclegrowththroughcAMP-andcGMP-dependentPKAandPKGpathways.

CompoundLibraries

BAY41-2272isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	360.39
Formula	C₂₀H₁₇FN₆
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	256376-24-6
PubChemID	9798973
InChIKey	ATOAHNRJAXSBOR-UHFFFAOYSA-N
Smiles	FC(C=CC=C3)=C3CN2N=C(C4=NC=C(C5CC5)C(N)=N4)C1=CC=CN=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	36.04	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight360.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.77mL	13.87mL	27.75mL
5mM	0.55mL	2.77mL	5.55mL
10mM	0.28mL	1.39mL	2.77mL
50mM	0.06mL	0.28mL	0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

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ProductDatasheets