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4000-520-616
当前位置: 首页 > 产品中心 > Receptors > Tocris/BIBO 3304 trifluoroacetate/2412/10/10 mg
商品详细Tocris/BIBO 3304 trifluoroacetate/2412/10/10 mg
Tocris/BIBO 3304 trifluoroacetate/2412/10/10 mg
Tocris/BIBO 3304 trifluoroacetate/2412/10/10 mg
商品编号: 2412/10
品牌: Tocris Bioscience
市场价: ¥5900.00
美元价: 3540.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:HighlyselectiveNPYY1receptorantagoNIST
ChemicalName:N-[(1R)-1-[[[[4-[[(Aminocarbonyl)amino]methyl]phenyl]methyl]amino]carbonyl]-4-[(aminoiminomethyl)amino]butyl]-α-phenyl-benzeneacetamideditrifluoroacetate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityNPYY1receptorantagonist(IC50valuesare0.38and0.72nMathumanandratreceptorsrespectively)thatdisplays>2600-foldselectivityoverY2,Y4andY5receptors.InhibitsNPY-andfasting-inducedfeedinginvivofollowingcentraladministration.Alsoantagonizesanxiolytic-likeeffectsofNPY.

CompoundLibraries

BIBO3304trifluoroacetateisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt757.69
FormulaC29H35N7O3.2CF3CO2H
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber191868-14-1
PubChemID5311022
InChIKeyTVMJSGGZULFVCZ-XMMPIXPASA-N
SmilesOC(=O)C(F)(F)F.OC(=O)C(F)(F)F.NC(=N)NCCC[C@@H](NC(=O)C(C1=CC=CC=C1)C1=CC=CC=C1)C(=O)NCC1=CC=C(CNC(N)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO75.77100
ethanol75.77100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight757.69.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.32mL6.6mL13.2mL
5mM0.26mL1.32mL2.64mL
10mM0.13mL0.66mL1.32mL
50mM0.03mL0.13mL0.26mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet