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当前位置: 首页 > 产品中心 > DNA_polymerase > Tocris/BIBR 1532/2981/50/50 mg
商品详细Tocris/BIBR 1532/2981/50/50 mg
Tocris/BIBR 1532/2981/50/50 mg
Tocris/BIBR 1532/2981/50/50 mg
商品编号: 2981/50
品牌: Tocris Bioscience
市场价: ¥15100.00
美元价: 9060.00
产地: 美国(厂家直采)
公司:
产品分类: DNA聚合酶
公司分类: DNA_polymerase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Selectivetelomeraseinhibitor
ChemicalName:2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl1-yl]amino]benzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivetelomeraseinhibitor(IC50valuesare93,>100000and>100000nMforhumantelomerase,humanRNApolymeraseIandhumanRNApolymeraseII+IIIrespectively).CausestelomereshorteninginexponentiallygrowingNCI-H460lungcarcinomacellsandeventualgrowtharrest.

CompoundLibraries

BIBR1532isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt331.36
FormulaC21H17NO3
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber321674-73-1
PubChemID9927531
InChIKeyPGFQXGLPJUCTOI-WYMLVPIESA-N
SmilesC/C(C2=CC1=CC=CC=C1C=C2)=CC(NC3=C(C(O)=O)C=CC=C3)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO33.14100
ethanol8.2825

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight331.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.02mL15.09mL30.18mL
5mM0.6mL3.02mL6.04mL
10mM0.3mL1.51mL3.02mL
50mM0.06mL0.3mL0.6mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet