Tocris/BMS 195614/3660/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/BMS 195614/3660/10/10 mg

Tocris/BMS 195614/3660/10/10 mg

商品编号： 3660/10

品牌： Tocris Bioscience

市场价： ¥4500.00

美元价： 2700.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveRARαantagoNIST

AlternativeNames:BMS614

ChemicalName:4-[[[5,6-Dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]benzoicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Neutralretinoicacidreceptor(RAR)α-selectiveantagonist(K_i=2.5nM).Displaysnosignificanteffectonnuclearreceptorcorepressor(NCoR)binding;moderatelydecreasesSMRTbindingtoRAR.Antagonizesagonist-inducedcoactivator(CoA)recruitment.

TechnicalData

M.Wt	448.51
Formula	C₂₉H₂₄N₂O₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	253310-42-8
PubChemID	445091
InChIKey	WGLMBRZXZDAQHP-UHFFFAOYSA-N
Smiles	O=C(NC4=CC=C(C(O)=O)C=C4)C3=CC1=C(C=C3)C(C)(C)CC=C1C2=CN=C(C=CC=C5)C5=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	11.21	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight448.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.23mL	11.15mL	22.3mL
5mM	0.45mL	2.23mL	4.46mL
10mM	0.22mL	1.11mL	2.23mL
50mM	0.04mL	0.22mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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