Tocris/BMS 345541/4806/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/BMS 345541/4806/50/50 mg

Tocris/BMS 345541/4806/50/50 mg

商品编号： 4806/50

品牌： Tocris Bioscience

市场价： ¥19300.00

美元价： 11580.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveallostericinhibitorofIKK;anti-inflammatory

ChemicalName:N¹-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediaminehydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveallostericinhibitorofIKK(IC₅₀valuesare0.3and4.0μMforIKKβandIKKαrespectively).Exhibitsnoeffectagainstapanelof15otherkinases.AttenuatesLPS-inducedcytokineproductioninvitroandblocksNFκBdependenttranscriptioninmice.Alsosuppressesjointdestructioninamousemodelofarthritis.

CompoundLibraries

BMS345541isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	291.78
Formula	C₁₄H₁₇N₅.HCl
Storage	Storeat-20°C
Purity	≥99%(HPLC)
CASNumber	547757-23-3
PubChemID	9926054
InChIKey	MIDKPVLYXNLFGZ-UHFFFAOYSA-N
Smiles	NCCNC1=NC3=C(C=C(C)C=C3)N2C1=NC=C2C.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	29.18	100
	water	29.18	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight291.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.43mL	17.14mL	34.27mL
5mM	0.69mL	3.43mL	6.85mL
10mM	0.34mL	1.71mL	3.43mL
50mM	0.07mL	0.34mL	0.69mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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