Tocris/BMS 566419/5492/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/BMS 566419/5492/50/50毫克

Tocris/BMS 566419/5492/50/50毫克

商品编号： 5492/50

品牌： Tocris Bioscience

市场价： ¥15300.00

美元价： 9180.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Inosinemonophosphatasedehydrogenase(IMPDH)inhibitor

ChemicalName:N-[1-[6-(4-Ethyl-1-piperazinyl)-3-pyridinyl]-1-methylethyl]-2-fluoro-9,10-dihydro-9-oxo-3-acridinecarboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentinosinemonophosphatedehydrogenase(IMPDH)inhibitor(IC₅₀=17nM).InhibitsproliferationofhumanT-lymphoblastsandPBMCsinvitro.Reducespawswellinginaratadjuvantarthritismodel.Orallyavailable.

CompoundLibraries

BMS566419isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	487.57
Formula	C₂₈H₃₀FN₅O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	566161-24-8
PubChemID	9913339
InChIKey	XEVJUIZOZCFECP-UHFFFAOYSA-N
Smiles	O=C2C3=C(C=C(C(NC(C)(C)C4=CC=C(N5CCN(CC)CC5)N=C4)=O)C(F)=C3)NC1=CC=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	24.38	50
	DMSO	48.76	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight487.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.05mL	10.25mL	20.51mL
5mM	0.41mL	2.05mL	4.1mL
10mM	0.21mL	1.03mL	2.05mL
50mM	0.04mL	0.21mL	0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

PreparingStockSolutions

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