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当前位置: 首页 > 产品中心 > Other_reagents > Tocris/BTT 3033/4724/50/50 mg
商品详细Tocris/BTT 3033/4724/50/50 mg
Tocris/BTT 3033/4724/50/50 mg
Tocris/BTT 3033/4724/50/50 mg
商品编号: 4724/50
品牌: Tocris Bioscience
市场价: ¥17580.00
美元价: 10548.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Selectiveinhibitorofintegrinα2β1
ChemicalName:1-(4-Fluorophenyl)-N-methyl-N-[4[[(phenylamino)carbonyl]amino]phenyl]-1H-pyrazole-4-sulfonamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveinhibitorofintegrinα2β1(EC50=130nMforα2β1bindingtocollagenI).Bindstotheα2Idomain.Exhibitsselectivityforα2β1overintegrinsα3β1,α4β1,α5β1andαv.InhibitsplateletaggregationtocollagenIcoatedcapillariesunderflow.Alsoinhibitsbindingofα2-expressingCHOcellstocollagenIundershearstressconditions.

CompoundLibraries

BTT3033isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt465.5
FormulaC23H20FN5O3S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1259028-99-3
PubChemID49841251
InChIKeyNSLIQOPYDUKWTA-UHFFFAOYSA-N
SmilesFC1=CC=C(N2N=CC(S(N(C3=CC=C(NC(NC4=CC=CC=C4)=O)C=C3)C)(=O)=O)=C2)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO46.55100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight465.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.15mL10.74mL21.48mL
5mM0.43mL2.15mL4.3mL
10mM0.21mL1.07mL2.15mL
50mM0.04mL0.21mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet