Biological Activity
Selective 5-HT2B receptor agonist.
Technical Data
| M. Wt | 322.85 |
| Formula | C16H18N2OS.HCl |
| Storage | Desiccate at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 160521-72-2 |
| PubChem ID | 5311036 |
| InChI Key | PYJBJMIBANAOFJ-UHFFFAOYSA-N |
| Smiles | Cl.CC(N)CC1=CNC2=CC=C(OCC3=CC=CS3)C=C12 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in DMSO |
Preparing Stock Solutions
The following data is based on the product molecular weight 322.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.1 mL | 15.49 mL | 30.97 mL |
| 5 mM | 0.62 mL | 3.1 mL | 6.19 mL |
| 10 mM | 0.31 mL | 1.55 mL | 3.1 mL |
| 50 mM | 0.06 mL | 0.31 mL | 0.62 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Kennett et al (1997) BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats. Neuropharmacology 36 233 PMID: 9144661
Kennett et al (1998) Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated. Neuropharmacology 37 1603 PMID: 9886683
Duxon et al (1997) Activation of 5-HT2B receptors in the medial amygdala causes anxiolysis in the social interaction test in the rat. Neuropharmacology 36 601 PMID: 9225285
Niebert et al (2011) Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network. PLoS One 6 e21395 PMID: 21789169
Keywords: BW 723C86 hydrochloride, supplier, 5-HT2B, agonist, Serotonin, Receptors, BW723C86, hydrochloride, 5-HT2B, Receptors, 5-HT2B, Receptors, Tocris Bioscience
