Tocris/BX 430/5545/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/BX 430/5545/50/50 mg

Tocris/BX 430/5545/50/50 mg

商品编号： 5545/50

品牌： Tocris Bioscience

市场价： ¥12580.00

美元价： 7548.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveP2X₄allostericantagoNIST

ChemicalName:N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveP2X₄allostericantagonist(IC₅₀=0.54μM).Exhibits>10-foldselectivityforhumanP2X₄receptorsoverP2X₁,P2X₂,P2X₃,P2X₅andP2X₇receptors.Bindsnoncompetitivelyatextracellularallostericsite.Effectiveathumanandzebrafish,butnotmouseandratP2X₄receptors.

TechnicalData

M.Wt	413.11
Formula	C₁₅H₁₅Br₂N₃O
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	688309-70-8
PubChemID	2810999
InChIKey	JFNKIJKRXKPQCC-UHFFFAOYSA-N
Smiles	CC(C)C1=CC(Br)=C(NC(NC2=CN=CC=C2)=O)C(Br)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	41.31	100
	ethanol	41.31	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight413.11.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.42mL	12.1mL	24.21mL
5mM	0.48mL	2.42mL	4.84mL
10mM	0.24mL	1.21mL	2.42mL
50mM	0.05mL	0.24mL	0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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