Tocris/BX 513 hydrochloride/2769/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/BX 513 hydrochloride/2769/50/50 mg

Tocris/BX 513 hydrochloride/2769/50/50 mg

商品编号： 2769/50

品牌： Tocris Bioscience

市场价： ¥16500.00

美元价： 9900.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveCCR1antagoNIST

AlternativeNames:VUF2274

ChemicalName:4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrilehydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveCCR1receptorantagonist(K_ivaluesare0.04,>10,>10and>10nMforCCR1,CCR5,CXCR2andCXCR4receptorsrespectively).InhibitsMIP-1α-inducedintracellularcalciummobilization(IC₅₀=2.5μM).AlsoafullinverseagonistatUS28,a HCMV-encodedchemokinereceptor.

TechnicalData

M.Wt	481.46
Formula	C₂₈H₂₉ClN₂O.HCl
Storage	Desiccateat+4°C
Purity	≥99%(HPLC)
CASNumber	1216540-18-9
PubChemID	56972186
InChIKey	SSZWNUGWOGONQJ-UHFFFAOYSA-N
Smiles	ClC1=CC=C(C2(O)CCN(CCCC(C4=CC=CC=C4)(C#N)C3=CC=CC=C3)CC2)C=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	48.15	100
	ethanol	24.07	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight481.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.08mL	10.39mL	20.77mL
5mM	0.42mL	2.08mL	4.15mL
10mM	0.21mL	1.04mL	2.08mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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