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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/BX 795/4318/10/10 mg
商品详细Tocris/BX 795/4318/10/10 mg
Tocris/BX 795/4318/10/10 mg
Tocris/BX 795/4318/10/10 mg
商品编号: 4318/10
品牌: Tocris Bioscience
市场价: ¥3980.00
美元价: 2388.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PDPK1(PDK1)inhibitor
ChemicalName:N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorof3-phosphoinositide-dependentkinase1(PDPK1).InhibitsAktphosphorylationatThr308inPC3cells;alsoinhibitsanchorage-independentgrowthofPC3andMDA-MB-468cells.Exhibitsactivityatotherkinases,includingTANK-bindingkinase1(TBK1),AuroraBandIκBkinaseε(IKKε).

TechnicalData

M.Wt591.47
FormulaC23H26IN7O2S
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber702675-74-9
PubChemID10077147
InChIKeyVAVXGGRQQJZYBL-UHFFFAOYSA-N
SmilesIC1=C(NCCCNC(C4=CC=CS4)=O)N=C(NC2=CC(NC(N3CCCC3)=O)=CC=C2)N=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO59.15100
ethanol59.15100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight591.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.69mL8.45mL16.91mL
5mM0.34mL1.69mL3.38mL
10mM0.17mL0.85mL1.69mL
50mM0.03mL0.17mL0.34mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet