Tocris/Bafilomycin A1/1334/10U/10 ug-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Bafilomycin A1/1334/10U/10 ug

Tocris/Bafilomycin A1/1334/10U/10 ug

商品编号： 1334/10U

品牌： Tocris Bioscience

市场价： ¥2580.00

美元价： 1548.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:H⁺-ATPase(vacuolar)inhibitor

ChemicalName:(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highlypotent,selectiveinhibitorofvacuolarH⁺-ATPases(IC₅₀=0.6-1.5nMinbovinechromaffingranules).Selectiveforv-ATPaseoverotherATPhydrolyzingenzymessuchasF-ATPasesandtheH⁺/K⁺-ATPase(P-ATPase).Thoughttoinhibitautophagyeitherbyblockingautophagosome-lysosomefusion(inH4IIEcells),orbyblockinglysosomaldegradation.

TechnicalData

M.Wt	622.84
Formula	C₃₅H₅₈O₉
Storage	Desiccateat-20°C
Purity	≥98%(HPLC)
CASNumber	88899-55-2
PubChemID	72311
InChIKey	WEEFNMFMNMASJY-UHFFFAOYSA-M
Smiles	O[C@H]([C@H](C)/C=C(C)/C=C1OC)[C@@H](C)C/C(C)=C/C=C[C@H](OC)C([C@@H](C)[C@H]([C@@H]([C@@]2(O)C[C@@H](O)[C@H](C)[C@@H]([C@H](C)C)O2)C)O)OC/1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	62.28	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight622.84.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.61mL	8.03mL	16.06mL
5mM	0.32mL	1.61mL	3.21mL
10mM	0.16mL	0.8mL	1.61mL
50mM	0.03mL	0.16mL	0.32mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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