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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/黄芩素/1761/50/50毫克
商品详细Tocris/黄芩素/1761/50/50毫克
Tocris/黄芩素/1761/50/50毫克
Tocris/黄芩素/1761/50/50毫克
商品编号: 1761/50
品牌: Tocris Bioscience
市场价: ¥1900.00
美元价: 1140.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:5-and12-Lipoxygenaseinhibitor
ChemicalName:5,6,7-Trihydroxy-2-phenyl-(4H)-1-benzopyran-4-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorof5-andplatelet12-lipoxygenases(IC50valuesare9.5and0.12μMrespectively).AlsoinhibitsRaf-mediatedMEK-1phosphorylationinC6ratgliomacellsandinducesG1andG2cellcyclearrestbydecreasingcdk1,cdk2,cyclinD2andcyclinAexpression.InhibitsproductionofinflammatorycytokinesbyinhibitingNF-κBactivation.

TechnicalData

M.Wt270.24
FormulaC15H10O5
StorageDesiccateat-20°C
Purity≥98%(HPLC)
CASNumber491-67-8
PubChemID5281605
InChIKeyFXNFHKRTJBSTCS-UHFFFAOYSA-N
SmilesOC1=C(O)C(O)=C2C(=O)C=C(OC2=C1)C1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO13.5150

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight270.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.7mL18.5mL37mL
5mM0.74mL3.7mL7.4mL
10mM0.37mL1.85mL3.7mL
50mM0.07mL0.37mL0.74mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet