Tocris/Balicatib/5585/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Balicatib/5585/50/50 mg

Tocris/Balicatib/5585/50/50 mg

商品编号： 5585/50

品牌： Tocris Bioscience

市场价： ¥12580.00

美元价： 7548.00

产地：美国(厂家直采)

公司：

产品分类：蛋白酶类

公司分类： protease

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectivecathepsinKinhibitor

ChemicalName:N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivecathepsinKinhibitor(IC₅₀valuesare1.4,56and480nMforhuman,ratandmousecathepsinK,respectively).Exhibits>300-foldselectivityforcathepsinKovercathepsinsL,BandS.LongtermsupratherapeuticdosingincreasestissuelevelsofcathepsinsLandBinrats.

CompoundLibraries

BalicatibisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	411.54
Formula	C₂₃H₃₃N₅O₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	354813-19-7
PubChemID	10201696
InChIKey	LLCRBOWRJOUJAE-UHFFFAOYSA-N
Smiles	O=C(NC1(CCCCC1)C(NCC#N)=O)C(C=C2)=CC=C2N3CCN(CCC)CC3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	41.15	100
	ethanol	4.12	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight411.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.43mL	12.15mL	24.3mL
5mM	0.49mL	2.43mL	4.86mL
10mM	0.24mL	1.21mL	2.43mL
50mM	0.05mL	0.24mL	0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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