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Tocris/3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride/0918/50/50 mg
Biological Activity
Potent inhibitor of dopamine uptake and transport (Ki = 11.8 nM).
Technical Data
| M. Wt | 379.88 |
| Formula | C21H23F2NO.HCl |
| Storage | Store at RT |
| CAS Number | 202646-03-5 |
| PubChem ID | 45260711 |
| InChI Key | YOORVSGDAHWVMC-UHFFFAOYSA-N |
| Smiles | Cl.CN1C2CCC1CC(C2)OC(C1=CC=C(F)C=C1)C1=CC=C(F)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 37.99 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 379.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.63 mL | 13.16 mL | 26.32 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
| 10 mM | 0.26 mL | 1.32 mL | 2.63 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.53 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Newman et al (1994) Novel 3α-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioural profiles. J.Med.Chem. 37 2258 PMID: 8057273
Newman et al (1995) Novel 4'-substituted and 4'4"-disubstituted 3α-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors. J.Med.Chem. 38 3933 PMID: 7562926
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