Tocris/Borrelidin/4706/1/1 mg-免疫在线蚂蚁淘旗下平台

当前位置：首页 > 产品中心 > Other_enzymes > Tocris/Borrelidin/4706/1/1 mg

商品详细Tocris/Borrelidin/4706/1/1 mg

Tocris/Borrelidin/4706/1/1 mg

商品编号： 4706/1

品牌： Tocris Bioscience

市场价： ¥7580.00

美元价： 4548.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:Antiangiogenic;inhibitsthreonyl-tRNAsynthetase

ChemicalName:(1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antibioticandantiangiogenic.Selectivelyinhibitsthreonyl-tRNAsynthetase(ThrRS).Exhibitsantiangiogenicactivityinamousemodeloftumorangiogenesis.Inducesapoptosisincapillarytube-formingendothelialcells;disruptscapillarytubesandinhibitstheirformation(IC₅₀=0.8nMinrataorta).Inducestheunfoldedproteinresponse(UPR)andapoptosisinoralcancercells.

TechnicalData

M.Wt	489.64
Formula	C₂₈H₄₃NO₆
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	7184-60-3
PubChemID	5357974
InChIKey	OJCKRNPLOZHAOU-SLNPHPKOSA-N
Smiles	O[C@@H](C1)[C@@H](C)C[C@@H](C)C[C@@H](C)C[C@H](C)[C@@H](O)C(C#N)=C/C=C/C[C@]([C@]2([H])CCC[C@H]2C(O)=O)([H])OC1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	0.98	2

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight489.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.04mL	10.21mL	20.42mL
5mM	0.41mL	2.04mL	4.08mL
10mM	0.2mL	1.02mL	2.04mL
50mM	0.04mL	0.2mL	0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

Selectanotherlanguage:

BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets