Tocris/Bz 423/5791/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Bz 423/5791/10/10 mg

Tocris/Bz 423/5791/10/10 mg

商品编号： 5791/10

品牌： Tocris Bioscience

市场价： ¥2900.00

美元价： 1740.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:ATPsynthaseinhibitor;proapoptotic

ChemicalName:7-Chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ATPsynthaseinhibitor(IC₅₀~5μM).Bindstheoligomycinsensitivityconferringprotein(OSCP)componentofmitochondrialF₁F₀-ATPaseinvitroresultingingenerationofsuperoxideandapoptosis.KillsprimaryBandTcellinmiceinvivo.Suppressesautoimmunityandprolongssurvivalinmouselupusmodel.

TechnicalData

M.Wt	440.92
Formula	C₂₇H₂₁ClN₂O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	216691-95-1
PubChemID	5497206
InChIKey	IJEUIRDNQUQMFU-UHFFFAOYSA-N
Smiles	CN1C2=CC=C(C=C2C(C3=CC=C(C=C3)O)=NC(C1=O)CC4=CC5=CC=CC=C5C=C4)Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	44.09	100
	ethanol	44.09	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight440.92.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.27mL	11.34mL	22.68mL
5mM	0.45mL	2.27mL	4.54mL
10mM	0.23mL	1.13mL	2.27mL
50mM	0.05mL	0.23mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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TechnicalData

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PreparingStockSolutions

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