Biological Activity
Endogenous human tachykinin-like peptide and potent agonist for NK1 receptors (EC50 = 1 nM).
Technical Data
| M. Wt | 1406.7 |
| Formula | C63H98N20O13S2 |
| Sequence |
RHRTPMFYGLM (Modifications: Met-11 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| PubChem ID | 90488729 |
| InChI Key | MMNLXHSWHPGRFE-MRQSSJIPSA-N |
| Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 1406.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.71 mL | 3.55 mL | 7.11 mL |
| 5 mM | 0.14 mL | 0.71 mL | 1.42 mL |
| 10 mM | 0.07 mL | 0.36 mL | 0.71 mL |
| 50 mM | 0.01 mL | 0.07 mL | 0.14 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Jiang et al (2003) PepPat, a pattern-based oligopeptide homology search method and the identification of a novel tachykinin-like peptide. Mamm.Genome 14 341 PMID: 12856286
Keywords: C14TKL-1, supplier, Endogenous, NK1, agonists, Tachykinin, Receptors, Neurokinin, Chromosome14, tachykinin-like, peptide1, Chromosome, 14, tachykinin-like, peptide, 1, NK1, Receptor, NK1, Receptor, Tocris Bioscience
