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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/CBR 5884/5836/50/50 mg
商品详细Tocris/CBR 5884/5836/50/50 mg
Tocris/CBR 5884/5836/50/50 mg
Tocris/CBR 5884/5836/50/50 mg
商品编号: 5836/50
品牌: Tocris Bioscience
市场价: ¥12580.00
美元价: 7548.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:3-Phosphoglyceratedehydrogenase(PHGDH)inhibitor
ChemicalName:Ethyl5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

3-Phosphoglyceratedehydrogenase(PHGDH)inhibitor(IC50=33μM).Decreasesdenovoserinesynthesisincancercells.InhibitsproliferationofcancercelllineshavinghighPHGDHexpressionlevels.

TechnicalData

M.Wt336.39
FormulaC14H12N2O4S2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber681159-27-3
PubChemID4674993
InChIKeyQBVIRPJBDIZKBC-UHFFFAOYSA-N
SmilesCCOC(C1=C(C(SC#N)=C(S1)NC(C2=CC=CO2)=O)C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO33.64100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight336.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.97mL14.86mL29.73mL
5mM0.59mL2.97mL5.95mL
10mM0.3mL1.49mL2.97mL
50mM0.06mL0.3mL0.59mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet