Tocris/CCMI/3837/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/CCMI/3837/10/10 mg

Tocris/CCMI/3837/10/10 mg

商品编号： 3837/10

品牌： Tocris Bioscience

市场价： ¥2580.00

美元价： 1548.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Positiveallostericmodulatorofα7nAChR

AlternativeNames:XY4083

ChemicalName:[N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Positiveallostericmodulatorofα7neuronalnicotinicacetylcholinereceptors(nAChR).Evokespositivemodulationofacetylcholine(ACh)-inducedEC₅currents(EC₅₀=0.7μM).Exhibitscognitive-enhancingpropertiesinrodentmodels;displaysnocytotoxiceffectsinPC12cellsorratprimarycorticalneurons.

CompoundLibraries

CCMIisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	388.25
Formula	C₁₉H₁₅Cl₂N₃O₂
Storage	Storeat-20°C
CASNumber	917837-54-8
PubChemID	67042344
InChIKey	VMAKIACTLSBBIY-UHFFFAOYSA-N
Smiles	CC1=NOC(=C1)C(=CNC1=CC=C(Cl)C=C1)C(=O)NC1=CC=C(Cl)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	38.83	100
	ethanol	3.88	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight388.25.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.58mL	12.88mL	25.76mL
5mM	0.52mL	2.58mL	5.15mL
10mM	0.26mL	1.29mL	2.58mL
50mM	0.05mL	0.26mL	0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

DilutionCalculator

ProductDatasheets