Biological Activity
For use in conjunction with [3H]-homoquinolinic acid to characterize NR2B-containing NMDA receptors; selectively inhibits [3H]-homoquinolinic acid binding to non-NMDA sensitive sites.
Technical Data
| M. Wt | 231.21 |
| Formula | C12H9NO4 |
| Storage | Desiccate at +4°C |
| CAS Number | 132623-44-0 |
| PubChem ID | 3337816 |
| InChI Key | IFXJDEHFADWURH-UHFFFAOYSA-N |
| Smiles | OC(=O)CC1=C(N=C2C=CC=CC2=C1)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. NaOH | 23.12 | 100mM with gentle warming | |
| DMSO | 23.12 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 231.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.33 mL | 21.63 mL | 43.25 mL |
| 5 mM | 0.87 mL | 4.33 mL | 8.65 mL |
| 10 mM | 0.43 mL | 2.16 mL | 4.33 mL |
| 50 mM | 0.09 mL | 0.43 mL | 0.87 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Brown et al (1998) [3H]-Homoquinolinate binds to a subpopulation of NMDA receptors and to a novel binding site. J.Neurochem. 71 1464 PMID: 9751179
Keywords: CCMQ, supplier, characterize, NR2B-containing, NMDA, receptors, Glutamate, Receptors, N-Methyl-D-Aspartate, iGlu, Ionotropic, NMDA, Receptors, NMDA, Receptors, Tocris Bioscience
