Tocris/CGH 2466 dihydrochloride/2344/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/CGH 2466 dihydrochloride/2344/10/10 mg

Tocris/CGH 2466 dihydrochloride/2344/10/10 mg

商品编号： 2344/10

品牌： Tocris Bioscience

市场价： ¥2780.00

美元价： 1668.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:A₁,A_2BandA₃antagoNISTandinhibitorofp38MAPKandPDE4

ChemicalName:4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolaminedihydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AdenosineA₁,A_2BandA₃receptorantagonist(IC₅₀valuesare19,21,and80nMrespectively).Alsoinhibitsp38MAPK(IC₅₀=187-400nM)andphosphodiesterasetype4D(IC₅₀=22nM).Displayspotentanti-inflammatoryeffectsinvitroandinvivo.Potentiallyusefulforasthmaandchronicobstructivepulmonarydisease(COPD)research.

TechnicalData

M.Wt	395.13
Formula	C₁₄H₉N₃SCl₂.2HCl
Storage	Desiccateat+4°C
Purity	≥99%(HPLC)
CASNumber	1177618-54-0
PubChemID	16759176
InChIKey	WHXRCTIBFLXKFD-UHFFFAOYSA-N
Smiles	Cl.Cl.NC1=NC(=C(S1)C1=CC=NC=C1)C1=CC(Cl)=C(Cl)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	3.95	10mMwithgentlewarming
	ethanol	1.98	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight395.13.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.53mL	12.65mL	25.31mL
5mM	0.51mL	2.53mL	5.06mL
10mM	0.25mL	1.27mL	2.53mL
50mM	0.05mL	0.25mL	0.51mL

ProductDatasheets

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