Tocris/CGP 74514 dihydrochloride/5472/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/CGP 74514 dihydrochloride/5472/10/10 mg

Tocris/CGP 74514 dihydrochloride/5472/10/10 mg

商品编号： 5472/10

品牌： Tocris Bioscience

市场价： ¥3100.00

美元价： 1860.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potentcdk1inhibitor

ChemicalName:rel-N²-[(1R,2S)-2-Aminocyclohexyl]-N⁶-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diaminedihydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentcdk1inhibitor(IC₅₀=25nM).ReducesAktphosphorylationandincreasesmitochondrialdamageinleukemiacellsinvitroincombinationwithLY294002.

CompoundLibraries

CGP74514dihydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxII.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	458.82
Formula	C₁₉H₂₄ClN₇.2HCl
Storage	DesiccateatRT
Purity	≥98%(HPLC)
PubChemID	121513864
InChIKey	YFAKNNUHXLCNLG-FZMMWMHASA-N
Smiles	CCN2C1=NC(N[C@@H]4CCCC[C@@H]4N)=NC(NC3=CC(Cl)=CC=C3)=C1N=C2.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	45.88	100
	water	22.94	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight458.82.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.18mL	10.9mL	21.8mL
5mM	0.44mL	2.18mL	4.36mL
10mM	0.22mL	1.09mL	2.18mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

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PreparingStockSolutions

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