Tocris/CITCO/3683/10/10毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/CITCO/3683/10/10毫克

Tocris/CITCO/3683/10/10毫克

商品编号： 3683/10

品牌： Tocris Bioscience

市场价： ¥2580.00

美元价： 1548.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveCARagoNIST

ChemicalName:6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Constitutiveandrostanereceptor(CAR)agonist(EC₅₀=49nM).Displays>100-foldselectivityoverPXRreceptorsandnoactivityatLXR,ERα,ERβ,PPAR,RAR,FXR,VDRandTHR.InducesCARnucleartranslocationandexpressionofCYP2B6inhepatocytesinvitro.

CompoundLibraries

CITCOisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	436.74
Formula	C₁₉H₁₂Cl₃N₃OS
Storage	Desiccateat-20°C
Purity	≥98%(HPLC)
CASNumber	338404-52-7
PubChemID	9600409
InChIKey	ZQWBOKJVVYNKTL-AUEPDCJTSA-N
Smiles	ClC(C(Cl)=C4)=CC=C4CO/N=C/C1=C(C3=CC=C(Cl)C=C3)N=C2N1C=CS2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	21.84	50
	ethanol	2.18	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight436.74.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.29mL	11.45mL	22.9mL
5mM	0.46mL	2.29mL	4.58mL
10mM	0.23mL	1.14mL	2.29mL
50mM	0.05mL	0.23mL	0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

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ProductDatasheets