Tocris/TAT环磷酰胺/5582/1/1毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/TAT环磷酰胺/5582/1/1毫克

Tocris/TAT环磷酰胺/5582/1/1毫克

商品编号： 5582/1

品牌： Tocris Bioscience

市场价： ¥4780.00

美元价： 2868.00

产地：美国(厂家直采)

公司：

产品分类：转录表达

公司分类： Target_Expression

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveHIF-1dimerizationinhibitor

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveHIF-1dimerizationinhibitor.Blocksprotein-proteininteractionofrecombinantHIF-1α,butnotHIF-2α,withHIF-1β(IC₅₀=1.3μM).Inhibitshypoxia-inducedHIF-1activity,anddecreasesVEGFandCAIXexpressioninosteosarcomaandbreastcancercellsinvitro.AlsoreducestubularizationofhypoxicHUVECs.

TechnicalData

M.Wt	2559.1
Formula	C₁₁₁H₁₈₈N₄₂O₂₄S₂
Sequence	CLLFVYCGRKKRRQRRRPPQ* (Modifications:Lactambridge:Cys-1toTyr-6),Disulfidebridge:1-1*)
Storage	Storeat-20°C
CASNumber	1446322-66-2
PubChemID	72192490
InChIKey	AWUUHEHYNQGEFC-XLZVTALKSA-N
Smiles	[H]N[C@@H](CSSC[C@@H]1N([H])C(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC1=O)C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto1mg/mlinwater

Solubility

Solubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight2559.1.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	0.39mL	1.95mL	3.91mL
5mM	0.08mL	0.39mL	0.78mL
10mM	0.04mL	0.2mL	0.39mL
50mM	0.01mL	0.04mL	0.08mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

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ProductDatasheets