4000-520-616
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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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4000-520-616
当前位置: 首页 > 产品中心 > Transporters > Tocris/CLP257/5242/50/50毫克
商品详细Tocris/CLP257/5242/50/50毫克
Tocris/CLP257/5242/50/50毫克
Tocris/CLP257/5242/50/50毫克
商品编号: 5242/50
品牌: Tocris Bioscience
市场价: ¥15100.00
美元价: 9060.00
产地: 美国(厂家直采)
公司:
产品分类: 转运体
公司分类: Transporters
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:SelectiveKCC2activator
ChemicalName:(5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveKCC2K+-Cl-cotransporteractivator(EC50=616nM).ExhibitsselectivityforKCC2overotherKCCfamilymembers,NKCC1andGABAAreceptors,aswellas55otherreceptors.EnhancesCl-transportandincreasesKCC2plasmamembraneexpressioninspinalsliceswithreducedKCC2function.Alleviateshypersensitivityinratswithperipheralnerveinjury.

TechnicalData

M.Wt307.34
FormulaC14H14FN3O2S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1181081-71-9
PubChemID44188931
InChIKeySKCADXVKQRCWTR-GHXNOFRVSA-N
SmilesOC1=C(/C=C2/C(N=C(N3CCCCN3)S2)=O)C=CC(F)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO30.73100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight307.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.25mL16.27mL32.54mL
5mM0.65mL3.25mL6.51mL
10mM0.33mL1.63mL3.25mL
50mM0.07mL0.33mL0.65mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet