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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/CMPD-1/2186/10/10 mg
商品详细Tocris/CMPD-1/2186/10/10 mg
Tocris/CMPD-1/2186/10/10 mg
Tocris/CMPD-1/2186/10/10 mg
商品编号: 2186/10
品牌: Tocris Bioscience
市场价: ¥3380.00
美元价: 2028.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Selectiveinhibitorofp38α-mediatedMK2aphosphorylation;alsotubulinpolymerizationinhibitor
ChemicalName:2'-Fluoro-N-(4-hydroxyphenyl)-[1,1'-biphenyl]-4-butanamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Non-ATP-competitive,selectiveinhibitorofp38α-mediatedMK2a(mitogen-activatedproteinkinase-2a)phosphorylation(apparentKi=330nM).Doesnotinhibitp38α-mediatedphosphorylationofMBPandATF-2.Alsotubulinpolymerizationinhibitor.CytotoxicinglioblastomacellsatconcentrationsthatdonotaffecttheMK2pathway.

CompoundLibraries

CMPD-1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt349.4
FormulaC22H20FNO2
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber41179-33-3
PubChemID11382492
InChIKeyODYAQBDIXCVKAE-UHFFFAOYSA-N
SmilesOC1=CC=C(NC(=O)CCCC2=CC=C(C=C2)C2=CC=CC=C2F)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO34.94100
ethanol34.94100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight349.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.86mL14.31mL28.62mL
5mM0.57mL2.86mL5.72mL
10mM0.29mL1.43mL2.86mL
50mM0.06mL0.29mL0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet