Tocris/CP 80633/2729/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/CP 80633/2729/50/50毫克

Tocris/CP 80633/2729/50/50毫克

商品编号： 2729/50

品牌： Tocris Bioscience

市场价： ¥15300.00

美元价： 9180.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectivePDE4inhibitor

ChemicalName:5-[3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl]tetrahydro-2(1H)-pyrimidinone

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveinhibitorofphosphodiesterasetype4(IC₅₀valuesare1.9,>100,>100,>100and>100μMforhumanlungPDE4,lungPDE1,lungPDE2,heartPDE3andplateletPDE-Vrespectively)thatdisplaysnosignificantPDE4isozymeselectivity.InhibitshydrolysisofcAMPinisolatedhumanperipheralbloodmonocytes,eosinophilsandTcells. Displaysanti-inflammatoryandbronchodilatoryeffectsinvivo.

TechnicalData

M.Wt	316.39
Formula	C₁₈H₂₄N₂O₃
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	135637-46-6
PubChemID	9861730
InChIKey	LITNEAPWQHVPOK-FFSVYQOJSA-N
Smiles	O=C(NC4)NCC4C1=CC(O[C@H]2C[C@@H]3CC[C@H]2C3)=C(OC)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	31.64	100
	ethanol	31.64	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight316.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.16mL	15.8mL	31.61mL
5mM	0.63mL	3.16mL	6.32mL
10mM	0.32mL	1.58mL	3.16mL
50mM	0.06mL	0.32mL	0.63mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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