Tocris/CPI 613/5348/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/CPI 613/5348/10/10 mg

Tocris/CPI 613/5348/10/10 mg

商品编号： 5348/10

品牌： Tocris Bioscience

市场价： ¥2580.00

美元价： 1548.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PDHandKGDHinhibitor

ChemicalName:6,8-Bis[(phenylmethyl)thio]octanoicacid

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Pyruvatedehydrogenase(PDH)andα-ketoglutaratedehydrogenase(KGDH)inhibitor.Disruptstumorcellmitochondrialmetabolism,andincreasesmitochondrialreactiveoxygenspecies(ROS)productioninH460lungcarcinomacells.HasnoeffectonKGDHactivityinnormalbronchialepithelialcells.Inducescelldeathofmultipletumorcelllinesselectivelyovernormalcellsinvitro.InhibitstumorgrowthofH460andBxPC-3tumorcellxenograftsinmice.

TechnicalData

M.Wt	388.59
Formula	C₂₂H₂₈O₂S₂
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	95809-78-2
PubChemID	24770514
InChIKey	ZYRLHJIMTROTBO-UHFFFAOYSA-N
Smiles	OC(CCCCC(SCC2=CC=CC=C2)CCSCC1=CC=CC=C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	38.86	100
	ethanol	38.86	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight388.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.57mL	12.87mL	25.73mL
5mM	0.51mL	2.57mL	5.15mL
10mM	0.26mL	1.29mL	2.57mL
50mM	0.05mL	0.26mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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