Tocris/CU CPT 4a/4883/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/CU CPT 4a/4883/10/10 mg

Tocris/CU CPT 4a/4883/10/10 mg

商品编号： 4883/10

品牌： Tocris Bioscience

市场价： ¥3980.00

美元价： 2388.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:SelectiveTLR3inhibitor

ChemicalName:N-[(3-Chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveTLR3inhibitor(IC₅₀=3.44μMinRAW264.7cells);suppressesdownstreamsignalingpathwaysmediatedbytheTLR3/dsRNAcomplex,inhibitingTNF-αandIL-1βproductioninwholecells.Reducesdeathofcryptcellsandimprovesgastrointestinalsyndromeinmice.

LicensingInformation

SoldunderlicensefromtheUniversityofColorado

CompoundLibraries

CUCPT4aisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	377.82
Formula	C₁₈H₁₃ClFNO₃S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1279713-77-7
PubChemID	53242268
InChIKey	IAASQMCXDRISAV-CYBMUJFWSA-N
Smiles	O=C(N[C@H](CC3=CC=CC=C3)[C@@](O)=O)C2=C(Cl)C1=CC=C(F)C=C1S2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.NaOH	18.89	50
	DMSO	37.78	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight377.82.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.65mL	13.23mL	26.47mL
5mM	0.53mL	2.65mL	5.29mL
10mM	0.26mL	1.32mL	2.65mL
50mM	0.05mL	0.26mL	0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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