Biological Activity
Potent neuropeptide Y (NPY) Y2 receptor antagonist (IC50 = 19 nM).
Licensing Information
Sold under license from The Scripps Research Institute
Technical Data
| M. Wt | 509.63 |
| Formula | C27H31N3O3S2 |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 1383478-94-1 |
| PubChem ID | 66561564 |
| InChI Key | VAUKHARIAMDAGF-UHFFFAOYSA-N |
| Smiles | OC(C2=CC=CC=C2)(C3=CC=CC=C3)C1CCN(C(NC4=CC=C(S(=O)(N(C)C)=O)C=C4)=S)CC1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 50.96 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 509.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.96 mL | 9.81 mL | 19.62 mL |
| 5 mM | 0.39 mL | 1.96 mL | 3.92 mL |
| 10 mM | 0.2 mL | 0.98 mL | 1.96 mL |
| 50 mM | 0.04 mL | 0.2 mL | 0.39 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Mittapalli et al (2012) Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonists. Bioorg.Med.Chem.Lett. 22 3916 PMID: 22607676
Keywords: CYM 9484, supplier, CYM9484, neuropeptides, Y, NPY, Y2, antagonists, potent, NPY, Receptors, NPY, Receptors, Tocris Bioscience
