Tocris/CZC 54252 hydrochloride/4534/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/CZC 54252 hydrochloride/4534/10/10 mg

Tocris/CZC 54252 hydrochloride/4534/10/10 mg

商品编号： 4534/10

品牌： Tocris Bioscience

市场价： ¥4180.00

美元价： 2508.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentLRRK2inhibitor;neuroprotective

ChemicalName:N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamidehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentinhibitorofleucine-richrepeatkinase2(LRRK2)(IC₅₀valuesare1.28nMand1.85nMforwild-typeandG2019SmutantformsofLRRK2respectively).AttenuatesneuronalinjuryinducedbyLRRK2-G2019Smutantactivityinprimaryhumanneurons(EC₅₀=1nM).

CompoundLibraries

CZC54252hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	541.45
Formula	C₂₂H₂₅ClN₆O₄S.HCl
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1191911-27-9
PubChemID	90488950
InChIKey	KWCBHUPLQMUKAF-UHFFFAOYSA-N
Smiles	ClC1=C(NC3=CC=CC=C3NS(C)(=O)=O)N=C(NC2=C(OC)C=C(N4CCOCC4)C=C2)N=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	54.15	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight541.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.85mL	9.23mL	18.47mL
5mM	0.37mL	1.85mL	3.69mL
10mM	0.18mL	0.92mL	1.85mL
50mM	0.04mL	0.18mL	0.37mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

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