Biological Activity
Oxytocin analog. Long-acting; displays agonist properties.
Technical Data
| M. Wt | 988.17 |
| Formula | C45H69N11O12S |
| Sequence |
XYIQNCPLG (Modifications: X = Butanoic acid, Gly-9 = C-terminal amide, Tyr-2 = Me-Tyr, Carba sulfide bridge between X-1 - Cys-6) |
| Storage | Store at -20°C |
| CAS Number | 37025-55-1 |
| PubChem ID | 71715 |
| InChI Key | SMMBGKXBHJTULT-DTRKZRJBSA-N |
| Smiles | CC[C@H](C)[C@@H]1NC(=O)[C@H](CC2=CC=C(O)C=C2)N(C)C(=O)CCCSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 29.65 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 988.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.01 mL | 5.06 mL | 10.12 mL |
| 5 mM | 0.2 mL | 1.01 mL | 2.02 mL |
| 10 mM | 0.1 mL | 0.51 mL | 1.01 mL |
| 50 mM | 0.02 mL | 0.1 mL | 0.2 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Su et al (2012) Carbetocin for preventing postpartum haemorrhage. Cochrane Database Syst.Rev. PMID: 22513931
Holleboom et al (2013) Carbetocin in comparison with oxytocin in several dosing regimens for the prevention of uterine atony after elective caesarean section in the Netherlands. Arch.Gynecol.Obstet. Epub ahead of print PMID: 23329341
Keywords: Carbetocin, supplier, Oxytocin, analog, octapeptide, agonists, Oxytocin, Receptors, Oxytocin, Receptors, Tocris Bioscience
