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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Target_Expression > Tocris/Chetomin/4705/1/1毫克
商品详细Tocris/Chetomin/4705/1/1毫克
Tocris/Chetomin/4705/1/1毫克
Tocris/Chetomin/4705/1/1毫克
商品编号: 4705/1
品牌: Tocris Bioscience
市场价: ¥3780.00
美元价: 2268.00
产地: 美国(厂家直采)
公司:
产品分类: 转录表达
公司分类: Target_Expression
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:BlocksinteractionofHIF-1α,HIF-2αandSTAT2withCBP/p300
ChemicalName:(3S,5aR,10bS,11aS)-2,3,5a,6,10b,11-hexahydro-3-(hydroxymethyl)-10b-(3-[(1S,4S)-3-[[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazABIcyclo[2.2.2]oct-1-yl)methyl]-1H-indol-1-yl]-2-methyl-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

TargetstheCH1domainofCBP/p300;inhibitsinteractionofHIF-1α,HIF-2αandSTAT2withCBP/p300.Attenuateshypoxia-inducedgeneexpressioninvitroandinvivo;rADIosensitizeshumanHT1080fibrosarcomacellsinvitro.

TechnicalData

M.Wt710.87
FormulaC31H30N6O6S4
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1403-36-7
PubChemID90488965
InChIKeyZRZWBWPDBOVIGQ-KIDIPURZSA-N
SmilesCN(C([C@@](CO)7N(C)C3=O)=O)[C@]3(SS7)CC2=CN([C@@]5(C[C@@](SS9)6C8=O)C4=CC=CC=C4N[C@@]([H])5N6C([C@@](CO)9N8C)=O)C1=CC=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight710.87.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.41mL7.03mL14.07mL
5mM0.28mL1.41mL2.81mL
10mM0.14mL0.7mL1.41mL
50mM0.03mL0.14mL0.28mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet