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Tocris Bioscience(优势品牌)
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当前位置: 首页 > 产品中心 > DNA_polymerase > Tocris/Costunolide/2483/1/1 mg
商品详细Tocris/Costunolide/2483/1/1 mg
Tocris/Costunolide/2483/1/1 mg
Tocris/Costunolide/2483/1/1 mg
商品编号: 2483/1
品牌: Tocris Bioscience
市场价: ¥1700.00
美元价: 1020.00
产地: 美国(厂家直采)
公司:
产品分类: DNA聚合酶
公司分类: DNA_polymerase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Inhibitorofhumantelomeraseactivity
ChemicalName:(3aS,6E,10E,11aR)-3a,4,5,8,9,11a-Hexahydro-6,10-dimethyl-3-methylene-cyclodeca[b]furan-2(3H)-one
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofhumantelomeraseactivity(IC50=65μMinMCF-7breastcancercells).Suppressesproliferationandinducesapoptosisinavarietyofhumantumorcelllines.SelectivelyblocksendothelialcellproliferationinducedbyVEGF.InhibitsexpressionofiNOSandIL-1βanddisruptsNF-κBactivation.Displaysanti-inflammatory,antifungalandantiviralproperties.

TechnicalData

M.Wt232.32
FormulaC15H20O2
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber553-21-9
PubChemID5281437
InChIKeyHRYLQFBHBWLLLL-AHNJNIBGSA-N
SmilesC/C1=C[C@@H](OC([C@]2=C)=O)[C@H]2CC/C(C)=C/CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO11.6250
ethanol11.6250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight232.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.3mL21.52mL43.04mL
5mM0.86mL4.3mL8.61mL
10mM0.43mL2.15mL4.3mL
50mM0.09mL0.43mL0.86mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet