Biological Activity
Agonist at mGlu1a and mGlu5a subtypes expressed in clonal RGT cell lines. Also agonist at NMDA and PLD-coupled mGlu receptors.
Technical Data
| M. Wt | 153.15 |
| Formula | C3H7NO4S |
| Storage | Desiccate at -20°C |
| CAS Number | 1115-65-7 |
| PubChem ID | 1549098 |
| InChI Key | ADVPTQAUNPRNPO-REOHCLBHSA-N |
| Smiles | [H][C@](N)(CS(O)=O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 15.31 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 153.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.53 mL | 32.65 mL | 65.3 mL |
| 5 mM | 1.31 mL | 6.53 mL | 13.06 mL |
| 10 mM | 0.65 mL | 3.26 mL | 6.53 mL |
| 50 mM | 0.13 mL | 0.65 mL | 1.31 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Gorman and Griffiths (1994) Sulphur-containing excitatory amino acid-stimulated inositol phosphate formation in primary cultures of cerebellar granule cells is mediated predominately by N-methyl-D-aspartate receptors. Neuroscience 59 299 PMID: 8008194
Kingston et al (1998) Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines. Neuropharmacology 37 277 PMID: 9681926
Mewett et al (1983) Pharmacology of the excitatory actions of sulphonic and sulphinic amino acids. CNS Receptors: From Molecular Pharmacology to Beha 163-174 PMID:
Keywords: L-Cysteinesulfinic acid, supplier, NMDA, mGlur, agonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Non-Selective, Metabotropic, NMDA, Receptors, Non-selective, mGlu, NMDA, Receptors, Tocris Bioscience
