Tocris/DBeQ/4417/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/DBeQ/4417/50/50 mg

Tocris/DBeQ/4417/50/50 mg

商品编号： 4417/50

品牌： Tocris Bioscience

市场价： ¥13300.00

美元价： 7980.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveandreversIBLep97ATPaseinhibitor

ChemicalName:N2,N4-Bis(phenylmethyl)-2,4-quinazolinediamine

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveandreversibleinhibitorofp97ATPase(VCP,IC₅₀=1.5μM).Inducesexecutionercaspases(caspase-3andcaspase-7)rapidly.Blocksthedegradationofendoplasmicreticulum-associateddegradation(ERAD)reporters;alsoblocksautophagosomematurationandpromotesaccumulationofLC3-II.

CompoundLibraries

DBeQisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	340.42
Formula	C₂₂H₂₀N₄
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	177355-84-9
PubChemID	676352
InChIKey	QAIMUUJJAJBPCL-UHFFFAOYSA-N
Smiles	C12=CC=CC=C1N=C(NCC4=CC=CC=C4)N=C2NCC3=CC=CC=C3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	34.04	100
	ethanol	6.81	20mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight340.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.94mL	14.69mL	29.38mL
5mM	0.59mL	2.94mL	5.88mL
10mM	0.29mL	1.47mL	2.94mL
50mM	0.06mL	0.29mL	0.59mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets