Tocris/DEL 22379/5774/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/DEL 22379/5774/50/50毫克

Tocris/DEL 22379/5774/50/50毫克

商品编号： 5774/50

品牌： Tocris Bioscience

市场价： ¥15100.00

美元价： 9060.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:ERKdimerizationinhibitor

ChemicalName:N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ERKdimerizationinhibitor(IC₅₀~0.5μM);inhibitsERKdimerizationwithoutaffectingphosphorylationorkinaseactivity.SuppressesgrowthoftumorcellsexpressingRAS-ERKoncogenesinvitro.Inducesapoptosisandpreventstumorprogressioninvivo.

TechnicalData

M.Wt	444.53
Formula	C₂₆H₂₈N₄O₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	181223-80-3
PubChemID	11224574
InChIKey	INQUULPXCZAKMS-XKZIYDEJSA-N
Smiles	O=C1NC2=CC=C(NC(CCN3CCCCC3)=O)C=C2/C1=C/C4=CNC5=C4C=C(OC)C=C5

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	22.23	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight444.53.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.25mL	11.25mL	22.5mL
5mM	0.45mL	2.25mL	4.5mL
10mM	0.22mL	1.12mL	2.25mL
50mM	0.04mL	0.22mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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