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当前位置: 首页 > 产品中心 > Receptors > Tocris/DG 172 dihydrochloride/5566/50/50 mg
商品详细Tocris/DG 172 dihydrochloride/5566/50/50 mg
Tocris/DG 172 dihydrochloride/5566/50/50 mg
Tocris/DG 172 dihydrochloride/5566/50/50 mg
商品编号: 5566/50
品牌: Tocris Bioscience
市场价: ¥14100.00
美元价: 8460.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentPPARβ/δinverseagoNIST;promotesBMCdifferentiation
ChemicalName:(αZ)-2-Bromo-α-[[4-(4-methyl-1-piperazinyl)phenyl]methylene]benzeneacetonitriledihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentPPARβ/δinverseagonist(IC50=26.9nM).InhibitsAngptl4geneexpressioninmousemyoblasts(IC50=9.5nM)invitro.AlsoaugmentsGM-CSF/IL-4-induceddifferentiationofmaturedendriticcellsfrombonemarrowcellsinculture.Orallyavailable.

CompoundLibraries

DG172dihydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt455.22
FormulaC20H20BrN3.2HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber1361504-77-9
PubChemID57342888
InChIKeySABUORLIDVBCPI-WTLOABTRSA-N
SmilesBrC(C=CC=C1)=C1/C(C#N)=C/C2=CC=C(N3CCN(C)CC3)C=C2.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO45.52100
water45.52100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight455.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.2mL10.98mL21.97mL
5mM0.44mL2.2mL4.39mL
10mM0.22mL1.1mL2.2mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet