Biological Activity
Broad spectrum glutamate receptor antagonist.
Technical Data
| M. Wt | 204.18 |
| Formula | C7H12N2O5 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 6729-55-1 |
| PubChem ID | 6604701 |
| InChI Key | ACIJGUBIMXQCMF-SCSAIBSYSA-N |
| Smiles | N[C@@]([H])([C@](O)=O)CCC(NCC(O)=O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in 1eq. NaOH and to 100 mM in water with gentle warming |
Preparing Stock Solutions
The following data is based on the product molecular weight 204.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.9 mL | 24.49 mL | 48.98 mL |
| 5 mM | 0.98 mL | 4.9 mL | 9.8 mL |
| 10 mM | 0.49 mL | 2.45 mL | 4.9 mL |
| 50 mM | 0.1 mL | 0.49 mL | 0.98 mL |
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References
References are publications that support the products' biological activity.
Aksenov et al (2005) Glutamate neurotransmission in the cerebellar interposed nuclei: involvement in classical conditioned eyeblinks and neuronal activity. J.Neurophysiol. 93 44 PMID: 15331619
Jones et al (1984) Structure-activity relations of dipeptide antagonists of excitatory amino acids. Neuroscience 13 573 PMID: 6392929
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