Tocris/DMH2/5580/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/DMH2/5580/50/50毫克

Tocris/DMH2/5580/50/50毫克

商品编号： 5580/50

品牌： Tocris Bioscience

市场价： ¥15300.00

美元价： 9180.00

产地：美国(厂家直采)

公司：

产品分类：氨基酸

公司分类： aminophenol

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:TypeIBMPreceptorinhibitor

ChemicalName:4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

TypeIBMPreceptorinhibitor(K_ivaluesare<1,5.4and43nMforALK6,ALK3andALK2,respectively).Exhibits>30-foldselectivityoverALK4,ALK5,BMPR2,AMPKandVEGFR2.AlsobindstoTGFBR2(K_i=85nM).DecreasesgrowthandinducescelldeathofH1299non-smallcelllungcarcinomacellsinvitro.Enhancesliverregenerationinvivo.

TechnicalData

M.Wt	451.52
Formula	C₂₇H₂₅N₅O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1206711-14-9
PubChemID	50997748
InChIKey	DXLXRNZCYAYUED-UHFFFAOYSA-N
Smiles	C(C=N2)(C3=CC=C(OCCN4CCOCC4)C=C3)=CN1C2=C(C5=CC=NC6=C5C=CC=C6)C=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	2eq.HCl	22.58	50
	DMSO	9.03	20mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight451.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.21mL	11.07mL	22.15mL
5mM	0.44mL	2.21mL	4.43mL
10mM	0.22mL	1.11mL	2.21mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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